Associate Professor Stuart Brierley is an NHMRC R.D Wright Biomedical Fellow at Flinders University and Head of the Visceral Pain Group at located at the South Australian Health and Medical Research Institute (SAHMRI).
He is an internationally recognised as an authority on the different afferent classes innervating the gut, the mechanotransduction channels underlying their function, the interaction of these channels with inflammatory mediators, and how this changes in acute and chronic pain.
A/Professor Brierley has a proven track record in coordinating multi-faceted research programs for high-impact publications in journal such as Nature, Nature Communications, Nature Reviews Gastroenterology and Hepatology, Gastroenterology, Gut and The Journal of Neuroscience.
His recent paper in Nature identified a crucial role for the voltage gated ion channel NaV1.1 in underlying the pathological pain associated with Irritable Bowel Syndrome. His recent collaborations with Industry partners identified the mechanism of pain relief of a new drug, linaclotide, in treating patient with Irritable Bowel Syndrome with Constipation (IBS-C). Linaclotide, a guanylate cyclase-C (GC-C) agonist is effective in relieving abdominal pain associated with IBS-C and is already available and registered for use by IBS-C patients in the USA and Europe.
A/Professor Brierly will explore NaV1.1 and its contribution to chronic visceral pain at APS 2017.
We are delighted to have Associate Professor Stuart Brierley involved in APS 2017, we hope you will be able to attend and enjoy everything this conference has to offer.
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